منابع مشابه
Structural motifs of biomolecules.
Biomolecular structures are assemblies of emergent anisotropic building modules such as uniaxial helices or biaxial strands. We provide an approach to understanding a marginally compact phase of matter that is occupied by proteins and DNA. This phase, which is in some respects analogous to the liquid crystal phase for chain molecules, stabilizes a range of shapes that can be obtained by sequenc...
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In recent years, much effort has been devoted to the measurement and modelling of the threedimensional structure and the folding abilities of biologically-relevant molecules, including neurotransmitters [1] and building blocks of deoxyribonucleic acid (DNA) [2]. Previous studies have shown that one can differentiate between the conformers of the same molecule by combing quantum computations wit...
متن کاملDna Structural Motifs
■ Abstract DNA secondary structure plays an important role in biology, genotyping diagnostics, a variety of molecular biology techniques, in vitro–selected DNA catalysts, nanotechnology, and DNA-based computing. Accurate prediction of DNA secondary structure and hybridization using dynamic programming algorithms requires a database of thermodynamic parameters for several motifs including Watson...
متن کاملIdentifying Structural Motifs in Proteins
In biological macromolecules, structural patterns (motifs) are often repeated across different molecules. Detection of these common motifs in a new molecule can provide useful clues to the functional properties of such a molecule. We formulate the problem of identifying a given structural motif (pattern) in a target protein (example) and discuss the notion of complete matches vis-a-vis partial ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2007
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0704594104